Eye movement desensitization and reprocessing for depressed individuals with multiple sclerosis: A pilot study (Multiple Sclerosis Journal)

Eye movement desensitization and reprocessing for depressed individuals with multiple sclerosis: A pilot study

This study examined the effectiveness of using the EMDR therapy protocol DeprEND to alleviate depression symptoms in people with multiple sclerosis.

Article Abstract

Background: Multiple studies have highlighted elevated rates of depression among individuals with Multiple Sclerosis (MS), with its associated symptoms posing a significant threat to overall well-being. Moreover, existing literature suggests a potential interconnection between depressive manifestations and the decline of physical functionalities in the context of MS.

Objective: to examine the viability of the Eye Movement Desensitization Reprocessing (EMDR) therapy protocol for the treatment of depressive disorders (DeprEND) for alleviating depression in individuals with MS.

Methods: We conducted a process–outcome study to examine the feasibilty and effectiveness DeprEND enrolling 13 individuals with MS and depressive symtpoms. Psychological and physical assessment pre-, post-intervention and 3-month follow-up were included. Pre- and post-magnetic resonance imaging (MRI) scans were conducted to analyze potential alterations in brain function.

Results: The EMDR DeprEND treatment showed a high level of adherence and feasibility. Significant reductions in depressive symptoms were found at post-intervention and at 3 months follow-up. No significant differences were observed in terms of physical symptoms. A significant modulation observed in parietal and premotor areas when examining negative valence stimuli post-treatment was found.

Conclusion: for The EMDR DeprEND protocol may represent a feasible and cost-effective treatment for reducing depressive symptoms in MS patients and improving their mental well-being.

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Rovaris, M., Toselli, E., Medozzi, L., Di Tell, S., Pirastru, A., Vlasi, V., Baglio, F., Ostacoli, L., D’Abramo, A., Incerti, A., Fernandez, I., Pagnini, F., & Cavalera, C. (2024). Eye movement desensitization and reprocessing for depressed individuals with multiple sclerosis: A pilot study. Multiple Sclerosis Journal, Online First. https://doi.org/10.1177/13524585241230236

About the Journal

“Multiple Sclerosis Journal is a peer-reviewed international journal that focuses on all aspects of multiple sclerosis, neuromyelitis optica and other related autoimmune diseases of the central nervous system. ”

—Description from publisher

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Eye movement desensitization and reprocessing for depressed individuals with multiple sclerosis: A pilot study (Multiple Sclerosis Journal)