Involvement of the cerebellum in EMDR efficiency: a metabolic connectivity PET study in PTSD
The posterior cerebellum and its metabolic connectivity with the precuneus are involved in the clinical efficiency of EMDR in PTSD.
Article Abstract
“Background: We recently reported an improvement of precuneus PET metabolism after EMDR therapy in military participants suffering from PTSD.
Objective: The aim of the present study was to investigate the metabolic changes of precuneus connectivity in these participants after such treatment.
Method: Fifteen participants with PTSD performed a brain 18F-FDG-PET sensitized by virtual reality exposure to war scenes, before and after EMDR treatment. Inter-regional correlation analysis was performed to study metabolic changes of precuneus connectivity through SPMT maps at whole-brain level (p < 0.005 for the voxel, p < 0.05 for the cluster).
Results: A decrease of connectivity was observed after EMDR between the precuneus and two significant bilateral clusters of the cerebellum (bilateral Crus I and VI cerebellar lobules, Tmax voxel of 5.8 and 5.3, and cluster size of 343 and 314 voxels, respectively). Moreover, higher cerebellar metabolism before treatment was associated with reduced clinical PTSD scores after EMDR (p = 0.03).
Conclusions: The posterior cerebellum and its metabolic connectivity with the precuneus are involved in the clinical efficiency of EMDR in PTSD.”
—Description from publisher
Article Access
Open Access
Verger, A., Rousseau, P. F., Malbos, E., Chawki, M. B., Nicolas, F., Lançon, C., Khalfa, S., & Guedj, E. (2020). Involvement of the cerebellum in EMDR efficiency: a metabolic connectivity PET study in PTSD. European Journal of Psychotraumatology, 11(1), 1767986. https://doi.org/10.1080/20008198.2020.1767986
Date
June 29, 2020
Creator(s)
A. Verger, P. F. Rousseau, E. Malbos
Contributor(s)
M. B. Chawki, F. Nicolas, C. Lançon, S. Khalfa, E. Guedj
Topics
PTSD
Practice & Methods
Mechanisms of Action, Neurobiology
Extent
7 pages
Publisher
Taylor & Francis
Rights
© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
APA Citation
Verger, A., Rousseau, P. F., Malbos, E., Chawki, M. B., Nicolas, F., Lançon, C., Khalfa, S., & Guedj, E. (2020). Involvement of the cerebellum in EMDR efficiency: a metabolic connectivity PET study in PTSD. European Journal of Psychotraumatology, 11(1), 1767986. https://doi.org/10.1080/20008198.2020.1767986
Audience
EMDR Therapists, Other Mental Health Professionals
Language
English
Content Type
Article, Peer-Reviewed
Access Type
External Resource, Open Access
