Post-traumatic stress in adults with 22q11.2 deletion syndrome
This study explored the occurrence of PTSD in individuals with 22q11.2DS and utilized EMDR therapy for treatment.
Article Abstract
“22q11.2 deletion syndrome (22q11.2DS) is associated with an elevated genetic risk of several psychiatric disorders. However, the prevalence of post-traumatic stress disorder (PTSD) in individuals with 22q11.2DS has been reported to be only 0.9%; this is lower than that of the general population (3.9%). We explored the occurrence of PTSD and traumatic events in a Dutch cohort of 112 adults with 22q11.2DS, and found PTSD in 8.0%, traumatic events in 20.5% and trauma-focused treatment in 17.9% of patients. Our novel findings suggest that PTSD may be underdiagnosed in individuals with 22q11.2DS. Clinicians and other caregivers should be alert to trauma in this population in order to enable treatment and minimise psychiatric burden.”
—Description from publisher
Article Access
Open Access
von Scheibler, E. N. M. M., van Amelsvoort, T. A. M. J., Vingerhoets, C., van Eeghen, A. M., & Boot, E. (2025). Post-traumatic stress in adults with 22q11.2 deletion syndrome. British Journal of Psychotherapy Open, 8, e126, 1-3. Open access: https://doi.org/10.1192/bjo.2022.525
About the Journal
“BJPsych Open is a high-quality, online-only open access journal for the publication of all methodologically sound research in psychiatry and disciplines related to mental health.”
—Description from publisher
Date
July 7, 2025
Creator(s)
Emma N. M. M. von Scheibler, Thérèse A. M. J. van Amelsvoort, Claudia Vingerhoets
Contributor(s)
Agnies M. van Eeghen, Erik Boot
Topics
PTSD
Publisher
Cambridge University Press
Rights
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of the Royal College of Psychiatrists. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
APA Citation
von Scheibler, E. N. M. M., van Amelsvoort, T. A. M. J., Vingerhoets, C., van Eeghen, A. M., & Boot, E. (2025). Post-traumatic stress in adults with 22q11.2 deletion syndrome. British Journal of Psychotherapy Open, 8, e126, 1-3. Open access: https://doi.org/10.1192/bjo.2022.525
Audience
EMDR Therapists, Other Mental Health Professionals
Language
English
Content Type
Article, Peer-Reviewed
Access Type
External Resource, Open Access
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