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Predicting optimal treatment outcomes in phase-based treatment and direct trauma-focused treatment among patients with posttraumatic stress disorder stemming from childhood abuse (Journal of Traumatic Stress)

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Home / Resources / Abuse/Neglect / Predicting optimal treatment outcomes in phase-based treatment and direct trauma-focused treatment among patients with posttraumatic stress disorder stemming from childhood abuse (Journal of Traumatic Stress)

Predicting optimal treatment outcomes in phase-based treatment and direct trauma-focused treatment among patients with posttraumatic stress disorder stemming from childhood abuse

This study examined efficacy of treatment, including EMDR therapy, for PTSD stemming from childhood abuse.


Article Abstract

“Research over the last few decades has demonstrated the effectiveness of various treatments for posttraumatic stress disorder (PTSD). However, the question of which treatment works best remains, especially for patients with PTSD stemming from childhood abuse. Using the Personalized Advantage Index (PAI), we explored which patients benefit more from phase-based treatment and which benefit more from direct trauma-focused treatment. Data were obtained from a multicenter randomized controlled trial (RCT) comparing a phase-based treatment condition (i.e., eye-movement desensitization and reprocessing [EMDR] therapy preceded by Skills Training in Affect and Interpersonal Regulation [STAIR]; n = 57) and a direct trauma-focused treatment (EMDR only; n = 64) among individuals with PTSD related to childhood abuse. Machine learning techniques were used to examine all pretreatment variables included in the trial as potential predictors and moderators, with selected variables combined to build the PAI model. The utility of the PAI was tested by comparing actual posttreatment outcomes of individuals who received PAI-indicated treatment with those allocated to a non–PAI-indicated treatment. Although eight pretreatment variables between PTSD treatment outcome and treatment condition were selected as moderators, there was no significant difference between participants assigned to their PAI-indicated treatment and those randomized to a non–PAI-indicated treatment, d = 0.25, p = .213. Hence, the results of this study do not support the need for personalized medicine for patients with PTSD and a history of childhood abuse. Further research with larger sample sizes and external validation is warranted.”

—Description from publisher

Article Access

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Bremer, S., van Vliet, N. I., Van Bronswijk, S., Huntjens, R., de Jongh, A., & van Dijk, M. K. (2023). Predicting optimal treatment outcomes in phase-based treatment and direct trauma-focused treatment among patients with posttraumatic stress disorder stemming from childhood abuse. Journal of Traumatic Stress, 36(6), 1044-1055. https://doi.org/10.1002/jts.22980

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Basic Info Collapse

Date
October 18, 2023

Creator(s)
Susanne Bremer, Noortje I. van Vliet, Suzanne Van Bronswijk

Contributor(s)
Rafaele Huntjens, Ad de Jongh, Maarten K. van Dijk

Topics
Abuse/Neglect, Childhood Trauma, PTSD

Practice & Methods
Comparative Studies

More Info Collapse

Extent
11 pages

Publisher
Wiley

Rights
© 2023 International Society for Traumatic Stress Studies.

APA Citation
Bremer, S., van Vliet, N. I., Van Bronswijk, S., Huntjens, R., de Jongh, A., & van Dijk, M. K. (2023). Predicting optimal treatment outcomes in phase-based treatment and direct trauma-focused treatment among patients with posttraumatic stress disorder stemming from childhood abuse. Journal of Traumatic Stress, 36(6), 1044-1055. https://doi.org/10.1002/jts.22980

Audience
EMDR Therapists, Other Mental Health Professionals

Language
English

Content Type
Article, Peer-Reviewed

Access Type
External Resource

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Cost-effectiveness analysis of the treatment of posttraumatic stress disorder related to childhood abuse: Comparison of phase-based treatment and direct trauma-focused treatment (Frontiers in Psychology)

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Phase-based treatment versus immediate trauma-focused treatment for post-traumatic stress disorder due to childhood abuse: Randomised clinical trial (BJPsych Open)

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