Recent neuroimaging studies on posttraumatic stress disorder (PTSD) have revealed a consistent decrease in thalamic activity, relative to non-PTSD controls. Empirical studies of the past decade have shown the thalamus to be centrally involved in the integration of perceptual, somatosensory, memorial, and cognitive processes (thalamo-cortical-temporal binding). A theoretical model is proposed to suggest that one underlying mechanism of EMDR stimulation (dual-attention stimulation/bilateral stimulation [DAS/BLS] ) is thalamic activation, specifically of the ventrolateral and central-lateral nuclei. It is hypothesized that this may facilitate the repair and integration of somatosensory, memorial, cognitive, frontal lobe and synchronized hemispheric functions that are disrupted in PTSD.