A control study of sertraline combined with the EMDR in the treatment of depression

目的 探讨舍曲林联合眼动脱敏和再加工治疗对抑郁症的临床疗效及安全性

Article Abstract

“目的 探讨舍曲林联合眼动脱敏和再加工治疗对抑郁症的临床疗效及安全性.方法 将64例抑郁症患者随机分为两组各32例,均给予舍曲林治疗,研究组联合眼动脱敏和再加工治疗,疗程均为6w.于治疗前及治疗第1 w、2 w、6 w末采用汉密顿抑郁量表、临床总体印象量表评定临床疗效,副反应量表评定不良反应.结果 治疗6 w末研究组有效率87.5%,对照组为84.4%,两组差异无显著性(χ2=0.129,P＞0.05).汉密顿抑郁量表、临床总体印象量表评分,研究组治疗1 w末均较对照组下降显著(P均＜0.05),2 w末均较对照组下降极显著(P均＜0.01),6 w末差异均无显著性(P均＞0.05).两组不良反应均轻微(P＞0.05).结论 舍曲林联合眼动脱敏和再加工治疗治疗抑郁症疗效显著,起效更快,安全性高,依从性好.”

[“Objective: To investigate the clinical efficacy and safety of sertraline combined with eye movement desensitization and reprocessing therapy in depression. Methods: A total of 64 patients with depression were randomly divided into two groups, with 32 cases in each group, all of whom were treated with sertraline, and the study group was treated with eye movement desensitization and reprocessing therapy, and the course of treatment was 6 w. The Hamilton Depression Rating Scale and the Clinical Global Impression Scale were used to evaluate the clinical efficacy before treatment and at the end of the 1st w, 2 w, and 6th w of treatment, and the adverse reactions were rated by the adverse reaction scale. Results: The effective rate of the study group was 87.5% at the end of 6 w, and 84.4% > the control group, and there was no significant difference between the two groups (χ2=0.129, P0.05>><<). Sertraline combined with eye movement desensitization and reprocessing therapy has significant efficacy in the treatment of depression, with faster onset, high safety and good compliance.”]

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Lei, S., & Zhenying, W. (2007). A control study of sertraline combined with the EMDR in the treatment of depression. Journal of Clinical Psychosomatic Diseases, 4, 307-308. Access link: https://caod.oriprobe.com/articles/12867831/A_control_study_of_sertraline_combined_with_the_EMDR_in_the_treatment_.htm