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EMDR versus waiting list in individuals at clinical high risk for psychosis with posttraumatic stress symptoms: A randomized controlled trial (Schizophrenia Research)

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Home / Resources / Psychosis/Schizophrenia / EMDR versus waiting list in individuals at clinical high risk for psychosis with posttraumatic stress symptoms: A randomized controlled trial (Schizophrenia Research)

EMDR versus waiting list in individuals at clinical high risk for psychosis with posttraumatic stress symptoms: A randomized controlled trial

Efficacy and safety of EMDR in individuals at clinical-high risk for psychosis with comorbid PTSD or subthreshold PTSD in an RCT.


Article Abstract

“Background: Post-traumatic stress disorder (PTSD) is highly prevalent in the individuals at clinical-high risk for psychosis (CHR). The aim of this study was to examine the efficacy and safety of Eye Movement Desensitization and Reprocessing (EMDR) in individuals at CHR with comorbid PTSD or subthreshold PTSD in a randomized controlled trial.

Methods: Fifty-seven individuals at CHR with PTSD or subthreshold PTSD formed the study sample. The eligible participants were randomly assigned to a 12 weeks EMDR treatment (N = 28) or a waiting list condition (WL, N = 29). The structured interview for psychosis risk syndrome (SIPS), the clinician administered post-traumatic stress disorder scale (CAPS) and a battery of self-rating inventories covering depressive, anxiety and suicidal symptoms were administered.

Results: Twenty-six participants in the EMDR group and all the participants in the WL group completed the study. The analyses of covariance revealed greater reduction of the mean scores on CAPS (F = 23.2, Partial η2 = 0.3, P < 0.001), SIPS positive scales (F = 17.8, Partial η2 = 0.25, P < 0.001) and all the self-rating inventories in the EMDR group than in the WL group. Participants in the EMDR group were more likely to achieve remission of CHR compared to those in the WL group at endpoint (60.7 % vs. 31 %, P = 0.025).

Conclusions: EMDR treatment not only effectively improved traumatic symptoms, but also significantly reduced the attenuated psychotic symptoms and resulted in a higher remission rate of CHR. This study highlighted the necessity of adding a trauma-focused component to the present approach of early intervention in psychosis.”

—Description from publisher

Article Access

Purchase/Subscription Required

Zhao, J., Chen, D-Y., Li, X-B., Xi, Y-J., Verma, S., Zhou, F-C., & Wang, C-Y. (2023). EMDR versus waiting list in individuals at clinical high risk for psychosis with posttraumatic stress symptoms: A randomized controlled trial. Schizophrenia Research, 256(1), 1-7. https://doi.org/10.1016/j.schres.2023.04.003

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Basic Info Collapse

Date
June 1, 2023

Creator(s)
Jie Zhao, Dong-Yang Chen, Xian-Bin Li

Contributor(s)
Ying-Jun Xi, Swapna Verma, Fu-Chun Zhou, Chuan-Yue Wang

Topics
Psychosis/Schizophrenia, PTSD

More Info Collapse

Extent
7 pages

Publisher
Elsevier

Rights
© 2023 Elsevier B.V. All rights reserved.

APA Citation
Zhao, J., Chen, D-Y., Li, X-B., Xi, Y-J., Verma, S., Zhou, F-C., & Wang, C-Y. (2023). EMDR versus waiting list in individuals at clinical high risk for psychosis with posttraumatic stress symptoms: A randomized controlled trial. Schizophrenia Research, 256(1), 1-7. https://doi.org/10.1016/j.schres.2023.04.003

Audience
EMDR Therapists, Other Mental Health Professionals

Language
English

Content Type
Article, Peer-Reviewed, RCT

Access Type
External Resource

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